Preparation of Shenkang Capsule and Its Clinical Study for Treatment of Latent Glomerulonephritis / 中成药

ABSTRACT

Objective:Shenkang was prescribed and prepared by our own hospital and its clinical effect and side effect for treating latent glomerulonephritis(LGN) were observed. Methods: Shenkang was composed of dog's penis Carapar Trionycis、nephritis herb and so on and prepared by the modern pharmaceutical technology. 60 cases with LGN were divided into the control group(30 cases) and the Shenkang group(30 cases) at random. Patients with protein uria in the control group were treated with the tablet of multiglycoside of Radix Tripterygii Wilfordi and patients with accompanied symptom were treated by the supportive expectant treatment. Patients in the Shenkang Capsule group were treated with it, 5 tables each time, 3 times a day and patients with accompanied symptom were also treated by the supportive expectant treatment. The treatment courses of two groups were all 3 months. 24 hour protein uria quantity、 serum total protein(TP)、 albumin(Al)、 1 hour urine red blood cell excreting rate(1huRBCer)、 serum creatinine and sodium before and after the treatment were observed. Results: Shenkang Capsule can significantly lower protein uria of LGN so as to raise the levels of TP and Al and reduce 1huRBCer. There was no side effect in the course of using Shenkang Capsule. Conclusion: Shenkang Capsule is effective for LGN.