Determination of in vitro Percutaneous Rate and in vitro of Release of Compound Patch of Hyperosteogeny / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Article
in Chinese
| WPRIM
| ID: wpr-681105
ABSTRACT
Objective:
To study the feasibility of percutaneous absorption of Compound Patch of Hyperosteogeny(CPH).Methods:
The content of ferulic acid,an index composition in percutaneous receptor fluid and release receptor fluid were determined by HPLC.Results:
The results of in vitro transdermal delivery experiment and in vitro release experiment showed that ferulic acid permeated at the constant speed of 0.2142?g?cm -2 ?h -1 in 24 hours and its release coincided with Higuchi Equation.Futhermore,the release rate was 14.53?g?cm -2 ?h -1/2 .Conclusion:
CPH is a skeleton controlledtransdermal delivery system whose permeation speed is limited by skin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional Patent Medicine
Year:
1992
Type:
Article
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