Application of Uniform Design in Supercritical Fluid Extraction of Rhizoma Alpiniae Officinarum / 中成药

ABSTRACT

Objective: To study the optimum extraction condition of effective composition in Rhizoma Alpiniae Officinarum by CO 2 supercritical fluid extraction. Methods: CO 2 supercritical fluid extraction condition was selected by uniform design. The extraction pressure, extraction temperature, analytic pressure, analytic temperature were four factors in the experiment. Seven levels of each factor were selected.Results: The optimum extraction condition in SFE was extraction pressure at 30MPa, extraction temperature at 32?C , analytic pressure at 6MPa, analytic temperature at 36?C . Conclusion: The method is simple, selective and efficient.