Study on stability in vitro of Andrographolide / 中成药
Chinese Traditional Patent Medicine
;
(12)1992.
Article
in Chinese
| WPRIM
| ID: wpr-681598
ABSTRACT
Objective:
In order to provide an effective reference to the study on its preparation, the stability in vitro of andrographolide was investigated.Methods:
Andrographolide was dissolved in phosphate buffer solutions of different pH values; classical isothermal method was employed; the content of andrographolide was determined by RP HPLC; then the stability of the drug in different biological media and organic solvents at 37?C was investigated.Results:
The stability of andrographolide was different at different pH values and was best in the condition of pH=3~5. In biological media, it was most stable in bovine serum and the next was in mice homogenate.Conclusion:
In different conditions, the stability of andrographolide was different. It provided a reference to the study on andrographolide and its preparation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Traditional Patent Medicine
Year:
1992
Type:
Article
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