Effect of ginkgo biloba extract on blood lipid in experimental hyperlipidmic quail / 中成药

ABSTRACT

Objective: To observe the effect of ginkgo biloba extract (GBE) (total ginkgo flavone 50% and qinkgolide 25%) on experimental hyperlipidemic quail.Methods: 60 quail were randomly grouped sixnormal group, hyperlipidemic model group and low, middle and high dose GBE groups, as well as lipanthyl group. Except for the normal group, the other five groups were firstly given high fat food for two weeks. Then among them, three groups were treated with GBE(20mg/kg?d, 40mg/kg?d, 80mg/kg?d, respectively) by ig administration, and one group was given lipanthyl(25mg/kg?d)by ig administration as the positve drug, another group was received aqua destillata by ig administration as the hyperlipidemic model. The treatments were consecutively carried out for four weeks. At the end, the vena jugularis externa blood of all the quail was taken and the serum lipid level of each quail was tested.Results: GBE in low dose group could significantly decrease the levels of TC, LDL C( P