Determination for 5-HMF in Glucose Injection containing the extract of Radix Salviae Miltiorrhizae / 中成药

ABSTRACT

Objective: To establish the determination for 5 HMF in Glucose Injection containing the extract of Radix Salviae Miltiorrhizae. Methods: Using HPLC with Hypersil ODS [4.6mm(i.d)?250mm] column, methanol 0.5% acetic acid as a mobile phase and detection wavelength at 284nm. Results: The peak of 5 hydroxymethylfurfural was separated from the peak of Danshensu. Conclusion: The method is simple, sensitive and accurate with a good reproducibility and can be used as the quality control for Glucose Injection containing the extract of Radix Salviae Miltiorrhizae.