Efficacy of home made hydrotalcite in treating bile reflux gastritis and 24-hour intragastric bile monitoring / 中华消化杂志

ABSTRACT

Objective To evaluate the efficacy and safety of two kinds of hydrotalcite, Weidimei and Talcid, in treating bile reflux gastritis. Methods Thirty patients with bile reflux gastritis confirmed by endoscopy were equally divided into experimental group (Weidimei) and control group (Talcid). The patients were given Weidimei or Talcid both at the dose of 1.0 g 3 times a day for 4 weeks, respectively. The severity of the symptoms including abdominal pain, regurgitation, nausea and vomiting of bile were investigated before and after the treatment. Twenty four hour bile in stomach was monitored. Results The severity of all symptoms greatly decreased after the treatment in two groups ( P