Protection of Sanqibaogan Capsules against the acute and chemical liver injury in mice / 中成药

ABSTRACT

AIM: To observe the liver protective effect of Sanqishentai Capsules (Radix Notoginseng, Herba Artemisiae Scopariae and Fructus ZiziphJujubae, etc.) in order to develop a series of compound Notoginseng. METHODS: By injecting CCl 4 in mouse's abdomen to cause the liver injury as model. The effect of the index of ALT, AST was mensurated that use the small, middle, big dosage of Sanqibaogan Capsules, at the same time the liver was examined in pathologic histology. RESULTS: The different dosages of Sanqishentai Capsules could obviously reduce the serum ALT, AST and the pathologic injury of the liver cells caused by CCl 4. CONCLUSION: Sanqibaogan Capsules have the obvious protection to the ocute and chemical liver injury of the mice.