Effects of Xinkeshu Capsule on Hemorheology of Rabbits with Experimental Diet ary Atherosclerosis / 中药新药与临床药理

ABSTRACT

Objective To study the effects of Xinkeshu capsule (mainly com po sed of Radix Salviae Miltiorrhizae, Radix Puerariae, Fructus Crataegi, Radix Not oginseng, Radix Auklandiae,etc.) on hemorheology of experimental atherosclerosis rabbits. Methods FASCO- 300 viscosity meter was used to detect whole blood v iscosity and plasma viscosity, hematocrit (Wen's tube) and erythrocyte sedimen tation (Wintrobe tube) were tested, and other items of hemorheology were exami ned. Results Xinkeshu capsule significantly inhibited the abnormal rise of who le blood viscosity, plasma viscosity, whole blood reduced viscosity, erythr ocyte aggregation index, erythrocyte sedimentation (ES), ES rate K, erythro cyte rigid index and Tk in the rabbits with atherosclerosis induced by high fat foodd( P