Study on the peritoneal dissemination of endometrial cells during hysteroscopy / 中华妇产科杂志

ABSTRACT

Objective To study prospectively the likelihood and the affecting factors of endometrial cell dissemination into the peritoneal cavity during hysteroseopie procedures.Methods A total of 121 patients with benign endometrial pathology underwent hysteroscopy combined with laparoseopy.All the patients had pelvic washings performed just before and after the procedure of hysteroscopy.We collected the peritoneal washings and analyzed the peritoneal cytology changes in both groups pre-and post-hysteroscopy, as well as the dissemination rate related to the time of hysteroscopy,the intrauterine distention pressure,the volume of distention media,and the feature of endometrial conditions.Results The ratio of positive endometrial cells in the peritoneal washings of post-hysteroscopy group was 51.2%(62/121),which was significantly higher than pre-hysteroscopy group,38.0%(46/121)(P0.05).Conclusions Hysteroseopic procedures may have a risk of disseminating the endometrial cells into peritoneal cavity.Under a certain uterine distention pressure,the rate of dissemination is correlated with hysteroscopie duration.