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Changes of serum cytokeratin 19 fragment in postoperative patients with non-small cell lung cancer / 中华全科医师杂志
Chinese Journal of General Practitioners ; (6)2005.
Article in Chinese | WPRIM | ID: wpr-683192
ABSTRACT
Objective To study the clinical value of serum cytokeratin 19 fragment (CYFRA21-1) as a biomarker in evaluating its prognosis,monitoring and follow-up of the postoperative patients with non- small cell lung cancer (NSCLC).Methods Serum CYFRA21-1 was determined by radioimmunoassay for 207 patients with NSCLC before and after surgical operation at Tongji Hospital,Shanghai.Relationship between serum CYFRA21-1 and the prognosis,recurrence and metastasis of lung cancer was analyzed retrospectively.Results The patients were followed-up for 37 months in average.Preoperative serum CYFRA21-1 was positive in 42.0% (87/207) of all the cases,48.8% (60/123) of squamous cell earcinama and 34.6% (27/78) of adenocarcinoma,with statistical significance (X~2=3.901,P

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of General Practitioners Year: 2005 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of General Practitioners Year: 2005 Type: Article