The Reverse Effect of Uygur Medicine ASMq on the Drug Resistance Cells of Liver Cancer / 中国中医药信息杂志
Chinese Journal of Information on Traditional Chinese Medicine
;
(12)2006.
Article
in Chinese
| WPRIM
| ID: wpr-683313
ABSTRACT
Objective To investigate the reverse effect of the extracted solution of uygur medicine ASMq on the liver cancer drug-resistance cell line Bel/Fu in vitro.Methods MTT assay was used to determine the IC50 of 5-Fu on Bel/Fu cell line and the reverse multiples of the drug-resistance before and after ASMq treatment.The concentration was used to determine the fold reversal of ASMq.By clone forming text to determine the reversal effect on drug resistance of Bel/Fu cell line.Results The IC50 value of ASMq crude extract was 2 000.68 ?g/mL.ASMq at 390 ?g/mL concentration was no toxic but had a coordinate effect on Bel/Fu cell line with 5-Fu.The fold reversal of ASMq combining with 5-Fu was 7.8,CDI was 0.89.The clone forming size became smaller comply with the concentration of ASMq.Conclusion ASMq has reversal effect on drug resistance of Bel/Fu cell line.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Information on Traditional Chinese Medicine
Year:
2006
Type:
Article
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