In-vitro Inhibitory Effects of Edomin on Herpes Simplex Virus TypeⅠ and Ⅱ / 广州中医药大学学报
Journal of Guangzhou University of Traditional Chinese Medicine
;
(6)2001.
Article
in Chinese
| WPRIM
| ID: wpr-683566
ABSTRACT
Objective To investigate the inhibitory effects of emodin on herpes simplex virus typeⅠandⅡ(HSV-Ⅰand HSV-Ⅱ)in vitro.Methods The antivirus effects of the derivates of anthraquinones component from rhubarb (emodin,rhein,physcion,aloeemodin,and chrysophanol)on HSV-Ⅰand HSV-Ⅱin rabbit renal cells were evaluated by means of the inhibition of cytopathic effect.Results Emodin can inhibit the cytopathic effect of HSV-Ⅰat the tolerance dosage of 3.75?g/mL and can inhibit the cytopathic effect of HSV-Ⅱat the tolerance dosage of 15.0?g/mL.Conclusion Emodin has in-vitro antivirus effects on herpes simplex virus typeⅠandⅡ,while other derivates such as rhein,physcion,aloe-emodin,chrysophanol have no such effects.
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Guangzhou University of Traditional Chinese Medicine
Year:
2001
Type:
Article
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