IMPROVEMENT OF NIGERICIN PRODUCTION IN STREPTOMYCES HYGROSCOPICUS NND-52 BY COMBINATION MUTANT / 微生物学通报
Microbiology
; (12)1992.
Article
in Zh
| WPRIM
| ID: wpr-684023
Responsible library:
WPRO
ABSTRACT
Based on the lethal rate, positive and negative mutation rate, the optimal doses of UV, HNO2, UV + AO treating S. hygroscopicus NND-52-29 were determined. The mutant strain A19 that was obtained showed the derepres-sive property to glucose and the nigericin yield of A19 could be increased by 128%. When it was subcultured combined with natural screening, its stability was rather satisfied.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Microbiology
Year:
1992
Type:
Article