The Effects of EGb and Venlafaxine on the Expression of nNOS and NO level in Rats of Depression Model / 中国心理卫生杂志
Chinese Mental Health Journal
;
(12)2002.
Article
in Chinese
| WPRIM
| ID: wpr-684329
ABSTRACT
Objective:
To observe the changes of hippocampus in the rats of depression model and study the protective effects of EGb (extracts of gingkobiloba) and Venlafaxine on brain injury.Methods:
Rats were divided into 6 groups. Groups A served as normal control. Group B?C?D?E?F received 21 days chronic stress. Group C?D?E?F were fed with normal food, EGb, Venlafaxine and EGb+Venlafaxine respectively for 28 days after enduring 21 days chronic stress. Every rat had been observed open-field behavior before decapitated.One side of the hippocampus were measured the expression of nNOS by immunohistochemistry method, the other side hippocampus and the serum were measured the concentrations of NO.Results:
The expression of protein nNOS in hippocampus of group B was increased compared with group A (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Mental Health Journal
Year:
2002
Type:
Article
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