Screening of Anti-tumor Activity from Ten Polypores Fungi in vitro / 微生物学通报

ABSTRACT

The anti-tumor activity of fermentation and the ethanol extraction of ten Polyprous fungi against human lung cancer cell NCI-H460 were determined by MTr method,the effect of medium and time for cultivation on the anti-tumor activity were studied.The results showed that the fermentation liquid of Onnia tomentosa and Ceizene unicolon and the mycelium ethanol extract of Formitopsis pinicola had obvious an- ti-tumor activity,the tumor inhibiting ratio of mycelium ethanol extract of Formitopsis pinicola cultivated in Potato-woodehipping medium was 88.87% at the concentration for 500?g/mL,and the inhibiting ratio had little change when Formitopsis pinicola cultivated in different medi- um and for different days.