Metabolic Syndrome Enhanced the Arteriosclerotic Development in Patients with Essential Hypertension / 中华高血压杂志

ABSTRACT

Objective To investigate the effects of metabolic syndrome(MS)on the structure and function of artery in patients with essential hypertension(EH).Methods One hundred forty-eight patients with EH were classified as EH with MS(EH+MS)or EH alone and healthy subjects(n=30)as control.Carotid intima-media thickness(IMT),brachial artery flow-mediated vasodilation(FMD)and non-flow-mediated vasodilation(NMD)were measured by Dopple ultrasonography.Results Carotid IMT(EH+MS1.0?0.3 vs EH0.8?0.2 vs control 0.5?0.1 mm)and hsCRP(EH+MS0.9?0.4 vs EH0.7?0.3 vs control0.4?0.2 mg/L)were significantly higher in EH+MS patients than that in EH+nonMS patients and control subjects(P all