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Study on the Interaction of Gliotoxin with BSA / 微生物学通报
Microbiology ; (12)2008.
Article in Chinese | WPRIM | ID: wpr-686337
ABSTRACT
The interaction between Gliotoxin and bovine serum albumin (BSA) was studied by the fluo-rescence, Circular Dichroism (CD) and ultraviolet visible (UV-Vis) techniques. The fluorescent experiment showed that the intrinsic fluorescence of BSA was quenched by the binding of gliotoxin in a static quenching procedure, with an association constant of 7.2?103 L/mol and in hydropobic forces. And the CD spectrum revealed that gliotoxin effected the conformation of BSA by increased the mass of ?-helix.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Microbiology Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Microbiology Year: 2008 Type: Article