CLINICAL FEATURES AND SITE DISTRIBUTION OF TONGUE CANCER / Шинэ санаа Шинэ нээлт

ABSTRACT

@#BACKGROUND: The incidence of oral cancer is differed in the world. Oral cancer incidence was high in Melanesia, South-Central Asia, East and Central European countries,3 while it was likely to be low in Africa, East Asia, and Central American countries. METHODS: The study was carried out by retrospective method, by using the medical reports obtained from the National Cancer Center of Mongolia. This study, based on retrospective method was conducted from medical reports of 68 patients who were diagnosed with squamous cell carcinoma of the tongue and at the Department of Head and Neck Surgery, Radio and Chemotherapy of the National Cancer Center of Mongolia between 2005 and 2014. The data was analyzed using SPSS 20.0 software; descriptive and detailed statistical analysis was made. Assumptions were examined by H2 testing method; it shall be statistically significant when P value is less than 0,05. RESULTS: The median age of the 68 patients at diagnosis was 58 years (range=31-85 years) and were 57% (39) men, 43% (29) women with a male to female ratio of 1.31 The most common cancer sub-sites reported were lateral border (60%) Considering the composite stage of the disease, 25% patients were in early stages (I-8.8% and II-16.2%) whereas 75% were in advanced stages (III- 36.8%, IVA- 20.6%, IVB-17.6%). At the time of presentation, majority of the patients had T3 lesions 44.1%, followed by T1 in 11.8%, T2 in 29.4%, T4 in 14.7%. Regional lymph node involvement was present in 54.4% (N1-25%, N2-17.6%, N3-11.8%) Considering the correlation between tumor size and cervical lymph node metastasis was present in 25% of of T1 tumours, 45% of T2 tumours, 66.7% of T3 tumours 60% of T4 tumours. There was no correlation between the tumor size at the primary site (T-status), and the presence of lymphatic spread (N-status) p=0.357. CONCLUSION: Our study showed that oral tongue cancer is majority occur in fifth and sixth of life and with a male predominance. Tongue cancer had more occurred at the lateral border (60%) and majority of the incidence (75%) is in the advanced stages III or IV. Based on the data in this study, it is possible to conclude that health education and health promotion must be encouraged by public health policies in order to diagnose in early stage and reduce the incidence and mortality rates of tongue cancer.