Impact of Smoking on Anal Abscess and Anal Fistula Diseases / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1034-1037, 2018.
Article
in English
| WPRIM
| ID: wpr-686986
ABSTRACT
<p><b>Background</b>Several studies have investigated the association between smoking and anal abscess and anal fistula (AA/F) diseases. However, the relationship between cigarette smoking and AA/F remains unclear. This study sought to assess the role of smoking in anorectal male patients in a Chinese population.</p><p><b>Methods</b>In this retrospective study, a questionnaire, including smoking history, was completed over a 3-month period by male inpatients in the Proctology Department of China-Japan Friendship Hospital. "Cases" were patients who had AA/F, and "controls" were patients with other anorectal complaints. Mann-Whitney U-test and Chi-square test were carried out to examine differences in baseline characteristics between groups. Subsequently, multivariate logistic regression was used to explore any related factors.</p><p><b>Results</b>A total of 977 patients aged from 18 to 80 years were included, excluding those diagnosed with inflammatory bowel disease or diabetes mellitus. Out of this total, 805 patients (82.4%) completed the entire questionnaire. Among the 805 patients, 334 (41.5%) were cases and 471 (58.5%) were controls. Results showed significant differences between cases and controls (χ = 205.2, P < 0.001), with smoking found to be associated with the development of AA/F diseases (odds ratio 12.331, 95% confidence interval 8.364-18.179, P < 0.001).</p><p><b>Conclusions</b>This study suggested smoking to be a potential risk factor for the development of AA/F diseases in a Chinese population. Consequently, current smoking patients should be informed of this relationship, and further research should be conducted to explore and investigate this further.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anus Diseases
/
Smoking
/
Logistic Models
/
Odds Ratio
/
Epidemiology
/
Surveys and Questionnaires
/
Retrospective Studies
/
Risk Factors
/
Rectal Fistula
Type of study:
Etiology study
/
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Medical Journal
Year:
2018
Type:
Article
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