Molecular mechanisms underlying daptomycin resistance / 生物工程学报
Chinese Journal of Biotechnology
;
(12): 832-838, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-687733
ABSTRACT
Due to potent bactericidal activity and low rate of drug-resistance, daptomycin is recognized as first line antibiotic to treat serious infections caused by drug-resistant Gram-positive pathogens. However, the incidence of daptomycin resistance is increasing due to its widespread application. Alteration of cell wall homeostasis and membrane phospholipid metabolism is involved in daptomycin resistance. The unique mode of action underlying daptomycin resistance in important pathogens, including Staphylococcus aureus and Enterococci, is presented in this paper.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Biotechnology
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS