Research advances on preventive and therapeutic effects of hydrogen on cardiovascular and cerebrovascular diseases and underlying mechanisms / 生理学报

ABSTRACT

For a long time, hydrogen (H) has been considered as a physiological inert gas. However, recent studies have demonstrated that molecular H exerts significant therapeutic effects on various disease models due to its antioxidative, anti-inflammatory and anti-apoptotic capabilities, which have also been well confirmed in many clinical trials. Cardiovascular and cerebrovascular diseases (CCVDs) are the leading cause of death in the world, constituting a serious threat to human life and public health. In this paper, we reviewed the latest research progress of the biomedical effects of H in CCVDs and its possible molecular mechanisms, in the hope of providing new clues for the treatment of some CCVDs.