Research Progress on Reversing Multidrug Resistance in Tumors by Using Chinese Medicine / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 474-480, 2018.
Article
in En
| WPRIM
| ID: wpr-687904
Responsible library:
WPRO
ABSTRACT
Multidrug resistance (MDR) is a major cause of cancer chemotherapy failure, and it is important to develop suitable reversal agents to overcome MDR. A majority of chemical reversal agents have acceptable reversal effects. However, the toxicity and adverse reactions associated with these agents restricts their clinical use. Chinese medicines (CMs) have lower toxicities and adverse reactions and are associated with multiple components, multiple targets and reduced toxicity. CMs have several advantages and could reverse MDR, decrease drug dosage, enhance patient compliance and increase efficacy. This review summarizes the current progress of CM reversal agents..
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
Research
/
Drugs, Chinese Herbal
/
Plant Extracts
/
Drug Resistance, Multiple
/
Drug Resistance, Neoplasm
Limits:
Humans
Language:
En
Journal:
Chinese journal of integrative medicine
Year:
2018
Type:
Article