Association between Hematologic Abnormalities and Severity in Neonate with NEC / 대한주산의학회잡지

ABSTRACT

OBJECTIVES: The purpose of this study is to evaluate the association between hematologic abnormalities and severity in neonate with NEC. METHODS: A retrospective chart review was established of 69 premature infants with a diagnosis of NEC who had been admitted to Pochon CHA University neonatal intensive care unit between Jan 2001 and Jun 2004. Infants were divided into three groups according to Bell's criteria. The association between perinatal and clinical manifestation, hematologic abnormalities and severity in neonate with NEC was evaluated. RESULTS: Nadir platelet counts, neutropenia, IT ratio, CRP and base excess were associated with severity of NEC, but coagulation disturbances (DIC) were not significantly correlated with severity of NEC. CONCLUSION: These preliminary results may be helpful to predict the severity and to improve the outcome in neonate with NEC.