Clinical study on Qingre Huayu Recipe for non-proliferative diabetic retinopathy / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM:To explore the efficacy of Qingre Huayu Recipe in the treatment of non-proliferative diabetic retinopathy(NPDR).<p>METHODS:We selected 84 cases of 84 eyes of NPDR patients diagnosed as “heat-blocking type” in the Department of Ophthalmology of our hospital during June 2016 to December 2017. According to the random number table method, 42 cases were divided into control group and experimental group respectively. On the basis of conventional hypoglycemic treatment, the control group was treated with calcium hydroxy benzene sulfonate capsules, and the observation group was treated with Qingre Huayu Recipe for 6wk. The improvement of visual acuity, fundus lesions and clinical efficacy before and after treatment were observed.<p>RESULTS:Before treatment, there was no significant difference in visual acuity between the two groups(<i>P</i>>0.05). After 6wk of treatment, the visual acuity of the experimental group(0.21±0.11)was significantly better than that of the control group(0.30±0.13), and the difference was statistically significant(<i>P</i><0.05). After 6wk of treatment, the fundus improvement efficiency and clinical efficacy(78.6% and 71.4%)were higher in the experimental group than in the control group(45.2% and 40.5%). There were significant differences in the improvement of fundus and clinical efficacy between the two groups(<i>P</i><0.05).<p>CONCLUSION:On the basis of traditional hypoglycemic treatment, Qingre Huayu Recipe has good curative effect on NPDR(heat-blocking type), which can improve the prognosis of patients. It is in line with syndrome differentiation and treatment, and provides ideas for Chinese medicine treatment of NPDR.