Research progress on pathobiology of myofibroblast in wound healing after glaucoma filtering surgery / 国际眼科杂志(Guoji Yanke Zazhi)
International Eye Science
;
(12): 1806-1809, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-688596
ABSTRACT
@#Glaucoma filtering surgery is the main treatment for the glaucomatous patients. Typically, surgery failed mary due to wound fibrosis and contracture at the post-surgical site.Myofibroblasts transdifferentiated from other cells via a process known as epithelial-mesenchymal transition(EMT)is a common feature of the fibrotic filtering channel, which can produce excessive amounts of the extracellular matrix(ECM), and then exert tractional forces, resulting in the disruption of tissue architecture and obstruction of filtering channel. In this review, we explain the pathological function of myofibroblast in the wound healing process after glaucoma filtering surgery.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Eye Science
Year:
2018
Type:
Article
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