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Perfusion Imaging of the Brain Using Z-Score and Dynamic Images Obtained by Subtracting Images from before and after Contrast Injection
Korean Journal of Radiology ; : 143-148, 2004.
Article in English | WPRIM | ID: wpr-68899
ABSTRACT

OBJECTIVE:

The aim of this study was to examine the feasibility of perfusion imaging of the brain using the Z-score and subtraction dynamic images obtained from susceptibility contrast MR images. MATERIALS AND

METHODS:

Five patients, each with a normal MRI, Moya-moya, a middle cerebral artery occlusion, post-trauma syndrome, and a metastatic brain tumor, were selected for a presentation. A susceptibility-contrast echo-planar image after a routine MRI was taken as the source image with a rapid manual injection of 0.1 mmol/kg of Gd-DTPA. The inflow and washout patterns were observed from the time-signal intensity curve of the serial scans using the standard program of an MRI machine. The repeated Z-score images of the peak and late phases were made using the threshold Z-score values between 1.4 and 2.0 in four to five studies of the pre-contrast, peak, and late phases. Dynamic subtraction images were produced by subtracting sequential post-contrast images from a pre-contrast image and coloring these images using a pseudocolor mapping method.

RESULTS:

In the diseases with perfusion abnormalities, the Z-score images revealed information about the degree of perfusion during the peak and late phases. However, the quality varied with the Z-score threshold and the studies selected in a group. The dynamic subtraction images were of sufficient quality with no background noise and more clearly illustrated the temporal changes in perfusion and delayed perfusion.

CONCLUSION:

The Z-scores and dynamic subtraction images illustrated the degree of perfusion and sequential changes in the pattern of perfusion, respectively. These images can be used as a new complimentary method for observing the perfusion patterns in brain diseases.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Brain / Feasibility Studies / Subtraction Technique / Magnetic Resonance Angiography / Contrast Media / Gadolinium DTPA Limits: Adult / Child / Female / Humans / Male Language: English Journal: Korean Journal of Radiology Year: 2004 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Brain / Feasibility Studies / Subtraction Technique / Magnetic Resonance Angiography / Contrast Media / Gadolinium DTPA Limits: Adult / Child / Female / Humans / Male Language: English Journal: Korean Journal of Radiology Year: 2004 Type: Article