Performance of the Paediatric Index of Mortality 3 and Paediatric Logistic Organ Dysfunction 2 Scores in Critically Ill Children
Annals of the Academy of Medicine, Singapore
;
: 285-290, 2018.
Article
in English
| WPRIM
| ID: wpr-690029
ABSTRACT
<p><b>INTRODUCTION</b>The Paediatric Index of Mortality 3 (PIM 3) and Paediatric Logistic Organ Dysfunction 2 (PELOD 2) scores were recently revised. We aimed to assess the performance of these scores in a contemporary cohort of critically ill children.</p><p><b>MATERIALS AND METHODS</b>This is a single-centre prospective study conducted in a multidisciplinary paediatric intensive care unit (PICU). Consecutive PICU admissions over 1 year were included and admission PIM 3 and PELOD 2 scores were calculated. The performance of each of the scores was evaluated by calculating the area under the curve (AUC) of the receiver operating characteristic (ROC) and the Hosmer-Lemeshow goodness-of-fit test for the outcome of PICU mortality.</p><p><b>RESULTS</b>A total of 570 patient admissions were eligible for this study. The median age of patients was 3.1 (interquartile range [IQR] 0.4, 8.9 years). Overall median PIM 3 and PELOD 2 scores were 1.2 (IQR 0.4, 3.2) % and 4 (IQR 2, 7), respectively. The overall mortality rate was 35/570 (6.1%). The PIM 3 and PELOD 2 scores had good discrimination for mortality (AUCs 0.88 [95% confidence interval (CI) 0.85, 0.91] and 0.86 [95% CI 0.83, 0.89], respectively). Goodness-of-fit was satisfactory for both scores. Higher PIM 3 and PELOD 2 scores were also associated with decreasing ventilator and PICU-free days.</p><p><b>CONCLUSION</b>PIM 3 and PELOD 2 scores are robust severity of illness scores that are generalisable to a contemporary cohort of critically ill children in Singapore.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
/
Prognostic study
Language:
English
Journal:
Annals of the Academy of Medicine, Singapore
Year:
2018
Type:
Article
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