The Prognostic Implication of Metabolic Syndrome in Patients with Heart Failure
Korean Circulation Journal
;
: 87-92, 2013.
Article
in English
| WPRIM
| ID: wpr-69106
ABSTRACT
BACKGROUND AND OBJECTIVES:
Metabolic syndrome (MetS) increases the risk of heart failure (HF). The purpose of this study was to identify the prevalence of MetS in patients with HF and determine the syndrome's association with HF in clinical and laboratory parameters. SUBJECTS ANDMETHODS:
A total of 3200 HF patients (67.6+/-14.5 years) enrolled in a nationwide prospective Korea HF Registry between Jan. 2005 and Oct. 2009. Patients were divided into two groups according to the presence or absence of MetS at admission group I (presence, n=1141) and group II (absence, n=2059).RESULTS:
The prevalence of MetS was 35.7% across all subjects and was higher in females (56.0%). The levels of white blood cells, platelets, creatinine, glucose, and cholesterol were significantly higher in group I than in group II. Left ventricular dimension and volume was smaller and ejection fraction was higher in group I than in group II. An ischemic cause of HF was more frequent in group I. The rates of valvular and idiopathic cause were lower in group I than in group II. The rate of mortality was lower in group I than in group II (4.9% vs. 8.3%, p<0.001).CONCLUSION:
Despite the increased cardiovascular risks in MetS, MetS was found to be associated with decreased mortality in HF.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Platelets
/
Cholesterol
/
Prevalence
/
Prospective Studies
/
Creatinine
/
Glucose
/
Heart
/
Heart Failure
/
Korea
/
Leukocytes
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Circulation Journal
Year:
2013
Type:
Article
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