Evaluation of Cardiac Functions with Tissue Doppler Imaging in Prediabetic Subjects
Korean Circulation Journal
;
: 82-86, 2013.
Article
in English
| WPRIM
| ID: wpr-69107
ABSTRACT
BACKGROUND AND OBJECTIVES:
The aim of the present study was to evaluate left ventricle systolic and diastolic function, using tissue Doppler echocardiography (TDE), in relation to blood glucose status in prediabetic patients who had no evidence of heart disease by conventional echocardiography (CE). SUBJECTS ANDMETHODS:
We included 60 patients (30 female, 30 male) and 20 healthy controls (10 male, 10 female). All participants were randomised into four groups according to their oral glucose tolerance test. Group-I consisted of those patients who had only impaired fasting glucose (IFG). group-II consisted of patients who had only impaired glucose tolerance (IGT) and group-III consisted of patients who had both IFG and IGT, that is so-called combined glucose intolerance. Group-IV included the healthy controls. All subjects underwent both CE and TDE.RESULTS:
No significant differences were found among the four groups in terms of CE. There was no significant difference between group-IV and group-I with respect to the early peak diastolic velocity (Ea) of medial mitral annulus (11.65+/-0.66 vs. 9.72+/-1.58, p>0.05), whereas a statistically significant difference was found between group-IV and group-II (11.65+/-0.66 vs. 9.06+/-1.07, p<0.001) and between group-IV and group-III (11.65+/-0.66 vs. 9.74+/-1.09, p<0.05).CONCLUSION:
Diastolic myocardial dysfunction in prediabetic patients may be identified by quantitative TDE before the appearance of CE indices of myocardial dysfunction.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Blood Glucose
/
Echocardiography
/
Echocardiography, Doppler
/
Fasting
/
Glucose Intolerance
/
Diabetes Mellitus, Type 2
/
Diabetic Cardiomyopathies
/
Glucose
/
Glucose Tolerance Test
/
Heart Diseases
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Circulation Journal
Year:
2013
Type:
Article
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