Arterial Ageing
Korean Circulation Journal
;
: 73-79, 2013.
Article
in English
| WPRIM
| ID: wpr-69109
ABSTRACT
Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiable causes of the arterial ageing process. Also, novel treatment targets derived from the disease models such as the Hutchinson Gilford Progeria Syndrome were reviewed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arteries
/
Progeria
/
Renin-Angiotensin System
/
Sclerosis
/
Aging
/
Oxidative Stress
/
Atherosclerosis
/
Vascular Stiffness
/
Pulse Wave Analysis
/
Hypertension
Language:
English
Journal:
Korean Circulation Journal
Year:
2013
Type:
Article
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