Is esophagectomy necessary for esophageal cancer patients with complete response after neoadjuvant chemoradiotherapy / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 983-986, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-691290
ABSTRACT
Esophageal cancer is one of the common cancers in China. More and more researches indicated that comprehensive treatment should be recommended for locally advanced esophageal cancer with resectable potential, especially the application of neoadjuvant chemoradiotherapy (CRT) was used to improve survival. However, the response to neoadjuvant chemoradiotherapy is various due to individual heterogeneity. Previous studies showed that pathological complete response (pCR) was considered as an important predictor of improved prognosis in esophageal cancer patients undergoing neoadjuvant CRT. Esophageal cancer patients with pCR had better prognosis than those without pCR. The watch and wait strategy may be a feasible option for surgically eligible rectal cancer patients with clinical complete response (cCR) after neoadjuvant chemoraidotherapy. Can the watch and wait strategy be used for reference to esophageal cancer? Whether patients with cCR following neoadjuvant CRT should undergo operation is analyzed in this article. According to present efficacy evaluation, cCR is inadequate to predict pCR. In addition, esophagectomy is favored for its curative effect and controllable complications. Therefore, we believe surgical resection, the chief component of multimodality treatment, should be recommended for all patients with locally advanced esophageal cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Esophageal Neoplasms
/
China
/
Survival Rate
/
Retrospective Studies
/
Treatment Outcome
/
Esophagectomy
/
Neoadjuvant Therapy
/
Chemoradiotherapy
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2018
Type:
Article
Similar
MEDLINE
...
LILACS
LIS