Predictors of Long-term Mortality after Hospitalization for Acute Exacerbation of COPD / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 205-214, 2006.
Article
in Korean
| WPRIM
| ID: wpr-69158
ABSTRACT
BACKGROUND:
Acute exacerbations form a major component of the socioeconomic burden of COPD. As yet, little information is available about the long-term outcome of patients who have been hospitalized with acute exacerbations, although high mortality rates have been reported. The aim of this study was to determine predictors of long-term mortality after hospitalization for acute exacerbation of COPD.METHODS:
We performed a retrospective cohort study of consecutive patients admitted to the hospital for COPD exacerbation between 2000 through 2004. Patients who had died in hospital or within 6-months after discharge, had tuberculosis scar, pleural thickening or bronchiectasis by chest radiography or had been diagnosed with malignancy during follow-up periods were excluded.RESULTS:
Mean age of patients was 69.5 years, mean follow-up duration was 49 months, and mean FEV1 was 1.00L (46% of predicted). Mortality was 35% (17/48). In the multivariate Cox regression analysis, heart rate of 100/min or more (p=0.003; relative risk [RR], 11.99; 95% confidence interval [CI], 2.34-61.44) and right ventricular systolic pressure (RVSP) of 35mmHg or more (p=0.019; RR, 6.85; 95% CI, 1.38-34.02) were independent predictors of mortality.CONCLUSION:
Heart rate and RVSP in stable state may be useful in predicting long-term mortality for COPD patients admitted to hospital with acute exacerbation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thorax
/
Tuberculosis
/
Blood Pressure
/
Bronchiectasis
/
Radiography
/
Retrospective Studies
/
Cohort Studies
/
Follow-Up Studies
/
Mortality
/
Cicatrix
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2006
Type:
Article
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