Distinct Clinical Characteristics of Unplanned Excision in Synovial Sarcoma
Clinics in Orthopedic Surgery
;
: 254-260, 2015.
Article
in English
| WPRIM
| ID: wpr-69212
ABSTRACT
BACKGROUND:
We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas.METHODS:
In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years. The clinicopathological characteristics and oncologic outcomes were compared.RESULTS:
The unplanned excision group showed longer duration of symptoms before diagnosis (p = 0.023), smaller lesion dimensions (p = 0.001), superficial location (p = 0.049), and predilection in the upper extremities (p = 0.037). Synovial sarcomas were most commonly misdiagnosed as neurogenic tumors (56%) in the upper extremities or as cystic masses (47%) in the lower extremities. Oncological outcomes, including disease-specific survival, metastasis-free survival, or local recurrence were not significantly different between the 2 groups (p = 0.159, p = 0.444, and p = 0.335, respectively). Repeated unplanned excision (p = 0.012) and delayed re-excision (p = 0.038) were significant risk factors for local recurrence in the unplanned excision group.CONCLUSIONS:
Synovial sarcomas treated with unplanned excision had distinct characteristics. These findings are important for developing diagnostic and therapeutic strategies for synovial sarcoma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Soft Tissue Neoplasms
/
Retrospective Studies
/
Treatment Outcome
/
Sarcoma, Synovial
Type of study:
Observational study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clinics in Orthopedic Surgery
Year:
2015
Type:
Article
Similar
MEDLINE
...
LILACS
LIS