NLRP12 and its role in occurrence and development of diseases / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 13-16, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-692429
ABSTRACT
NLRP12 is a member of the NOD-like receptors family in innate immune system,and plays an important role on resistance to intracellular pathogens.Once being activated,NLRP12 could recruit and combine with its downstream effector proteins into inflammasome,thus involving in pathogen clearance.Meanwhile,NLRP12 is one of the several anti-inflammatory molecules in the NOD-like receptors family.In this review,its structure,tissue distribution,function and association with diseases were discussed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2018
Type:
Article
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