MicroRNA-21 and bronchial asthma / 国际儿科学杂志

ABSTRACT

MicroRNAs are a class of small,single-stranded,highly conserved RNAs,which contributes to the regulation of growth,development,metabolism and disease.Recent studies have shown that a few microRNAs play a vital role in allergic inflammation with special focus on bronchial asthma.To investigate the regulation mechanism of microRNA-21 in the pathogenesis of asthma can help to find a safe,effective and specific therapy.In this paper,the role of miRNA-21 in the pathogenesis of asthma is reviewed.