Research progress of relationship between miRNA and neonatal lung injury / 国际儿科学杂志

ABSTRACT

Acute respiratory distress syndrome,bronchopulmonary dysplasia,and pulmonary fibrosis are common and serious diseases which affect the survival rate of preterm infants.MicroRNA (miRNA) can regulate the expression of genes through the target mRNA and affect the growth of lung tissue,participating in the process of lung injury-related diseases.In recent years,miRNA detection methods have been gradually improved,making it more feasible as a circulatory marker.This article summarizes recent progress of miRNA and lung injury in order to explore the relationship between miRNA with lung development and injury repair,and to expand the prevention and treatment in lung injury related diseases of preterm infants.