Rho kinase signal pathway and inflammatory bowel disease / 国际儿科学杂志

ABSTRACT

Rho/Rho-kinase signaling pathway is a ubiquitous one in vivo and plays a role of "molecular switch" by regulating the polymeric state of intracellular actin cytoskeleton and participates in the regulation of various cellular functions.As research continues,some of them have provided evidence of Rho kinase signal pathway function at the occurrence and development of inflammatory bowel disease.This review aims to summarize the relationship between Rho kinase signal pathway and inflammatory bowel disease.