Progress of caffeine in preventing bronchopulmonary dysplasia in preterm infants / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 743-746, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-692582
ABSTRACT
Caffeine is a methylxanthine,clinically used to treat apnea in preterm infants. However,it has been found that the drug also has a role in reducing the incidence of bronchopulmonary dysplasia( BPD) in pre-term infants in recent years. It may be related to improvement of lung function,improvement of extubation suc-cess rate and shortening of ventilator assisted ventilation time. Further study found that caffeine could play a pro-tective role in the prevention and control of BPD by antagonistic adenosine receptors, inhibiting inflammatory mediators,inhibiting the transforming growth factors-β1 ,and inhibiting matrix metalloproteinases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2018
Type:
Article
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