Analysis on the change of distribution of the major non-fermenting bacilli and the sensitivity of antibiotics from 2014 to 2016 / 国际检验医学杂志

ABSTRACT

Objective To investigate the distribution and antibiotics resistance of the major non-fermenting bacteria in our hospital from 2011 to 2016 ,then provide a reference for clinic practice .Methods Retrospective-ly analyze clinical distribution and antimicrobial susceptibility of 2398 non-fermenting bacteria from 2014 to 2016 .Results Over the past 3 years ,2398 main non fermented bacteria were isolated ,mainly 1019 strains of Acinetobacter Bauman (42 .5％ ) ,followed by Pseudomonas aeruginosa 1016 (42 .4％ ) .The main non fermen-tative bacteria isolated from ICU were 727 strains (30 .3％ ) ,ranking the first in all departments ,and the Acin-etobacter Bauman was the top .The sensitivity rate of Acinetobacter Bauman to antibiotics was decreasing year by year ,as low as 25 .0％ -40 .0％ .Especially in ICU ,the sensitivity rates were less than 10 .0％ .The suscep-tibility rates of Pseudomonas aeruginosa to a variety of antibiotics ,such as ceftazidime ,cefepime ,imipenem , ciprofloxacin ,levofloxacin ,were all increased ,and the sensitivity was >70 .0％ .Conclusion Acinetobacter and Pseudomonas aeruginosa were the main pathogenic bacteria in the clinical distribution of non fermenting bacte-ria .The most sensitive rate of the former to antibiotics was decreasing year by year ,especially the ICU situa-tion was severe ,the sensitivity of the latter was increasing year by year ,which was beneficial to the clinical se-lection of antimicrobial agents .