NT-proBNP,Hcy and hs-CRP levels in patients with acute coronary syndromes and its clinical significance / 国际检验医学杂志

ABSTRACT

Objective To investigate the levels of N-terminal B-type brain natriuretic peptide (NT-proB-NP) ,homocysteine (Hcy) and high-sensitivity C reactive protein (hs-CRP) in serum of patients with acute coronary syndromes and clinical significance .Methods Twenty hundred patients with acute coronary syn-dromes were enrolled in our hospital from March 2016 to February 2017 .Fifty patients with healthy subjects were selected as control .Serum samples were collected and immunocytochemistry Serum levels of NT-proB-NP ,Hcy and hs-CRP were measured by cyclic enzyme method and immunoturbidimetric turbidimetric assay . Results The levels of NT-proBNP ,Hcy and hs-CRP in serum of patients with acute coronary syndromes were significantly higher than those of healthy subjects .The positive rate of serum test was 91 .50% .The more seri-ous the disease and the higher the number of coronary lesions The levels of NT-proBNP ,Hcy and hs-CRP in patients with acute coronary syndromes were higher .Conclusion The combination of three serum markers coronary artery syndrome in the clinical diagnosis and treatment has important reference value .