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Vascular endothelial growth factor: a potential therapeutic target for ischemic stroke / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases ; (12): 47-50, 2018.
Article in Chinese | WPRIM | ID: wpr-692948
ABSTRACT
Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis and vascular regeneration after cerebral ischemia.On one hand,VEGF plays a neuroprotective effect by promoting angiogenesis and neurogenesis;on the other hand,VEGF induced endothelial permeability can cause blood-brain barrier (BBB) dysfunction.Exercise preconditioning can up-regulate the expression of VEGF and reduce the ischemic brain damage by enhancing the cerebral microvascular integrity.VEGF can be used as a therapeutic target for ischemic stroke.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Cerebrovascular Diseases Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: International Journal of Cerebrovascular Diseases Year: 2018 Type: Article