Therapeutic effect of ultra pulse carbon dioxide fractional laser on treating hypertrophic scar after burn / 国际生物医学工程杂志

ABSTRACT

Objective To study the therapeutic effect of ultra pulsed carbon dioxide fractional laser on treating hypertrophic scar after burn.Methods Forty-five patients with hypertrophic scar after burn were selected.Each laser treatment included an ultra-pulse mode and a Scaar FX mode scan irradiation,and the treatment wasconducted once a month for 4 to 6 times.In the ultra-pulse irradiation,the energy was 150～175 mJ,frequency was40 Hz,hole spacing was about 4～5 mm,and irradiation time per hole was 2～3 s,and in Scaar FX mode energy was60～150 mJ,frequency 250 Hz,and density 1％ to 3％.Before the first treatment and 6 months after the end of thetreatment,the Vancouver scar scale (VSS) was used to score the scar morphology,and the visual analog scale (VAS)was used to score the scar pain and itching.The effect of the treatment was classified as significant,effective andinvalid.In addition,adverse reactions occurred during the treatment were recorded.Results After six months of thetreatments,the VSS score,VAS pain score,and VAS pruritus score of the patients were 4.16±1.72,1.58±0.62,and1.24±0.74,respectively,while the pre-treatment values were 10.17±1.96,2.98±0.89,and 2.31±0.97,respectively.The differences were statistically significant (all P＜0.01).The treatment was effective in all patients,and the effectwas significant in 35 cases,effective in 10 cases,and no recurrence occurred within 6 months after treatment.In 3patients,blisters appeared on the scar after the first treatment,and the blister collapsed to form a wound.After thedressing change,the blisters healed after 7 to 10 days.Conclusion Ultra pulsed carbon dioxide fractional laser iseffective in treating hypertrophic scar after burn,with mild adverse reactions and no relapse,which is worthy ofclinical promotion.