Role of wild-type p53-induced phosphatase 1 in cancer / 国际外科学杂志
International Journal of Surgery
; (12): 785-788, 2018.
Article
in Zh
| WPRIM
| ID: wpr-693318
Responsible library:
WPRO
ABSTRACT
Wild-type p53-induced phosphatase 1 is a member of the protein phosphatase family and is an established oncogene due to its dephosphorylation of key protein in pathways and negative control of the DNA damage response system.Wild-type p53-induced phosphatase 1 serves a major role in tumorigenesis,progression,invasion,distant metastasis and chemotherapy resistance in various types of human cancer.Therefore,it may be a potential biomarker and therapeutic target in the diagnosis and treatment of cancer.In the paper,the current knowledge on the role of wild-type p53-induced phosphatase 1 in cancer is discussed.
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WPRIM
Language:
Zh
Journal:
International Journal of Surgery
Year:
2018
Type:
Article