Wnt signaling pathway in the neural stem cell proliferation and the herbal medicine intervention:research progress / 国际药学研究杂志

ABSTRACT

The characteristics of self-renewal and multilineage differentiation potential of neural stem cells(NSC)provide a new strategy for the treatment of ischemic brain sequelae.It is of great significance to find out new drugs that regulate the proliferation of endogenous NSC for the damage of nerve cells and the change of microenvironment in the brain.This review summarizes the prog?ress of Wnt signaling pathway in regulating NSC proliferation,related drug targets and the current research status of Chinese herbal medicines in regulating NSC proliferation,in order to provide a reference for future studies on new drugs for the prevention and treat?ment of ischemic brain sequelae.