Research advances of alpha-enolase in tumors / 国际肿瘤学杂志

ABSTRACT

Alpha-enolase(ENO1) is one of the key enzymes in glycolysis,which plays an important role in tumor metabolism.Accumulating evidences show that ENO1 is overexpressed in many tumor tissues,promoting cell proliferation,apoptosis,invasion and metastasis.It is also closely associated with drug resistance and tumor immunotherapy.As a novel potential target in tumor therapy,ENO1 has drawn great attention.