CRISPR/Cas9 genome editing system and its application in tumor therapy / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 556-560, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-693554
ABSTRACT
CRISPR/ Cas9 gene editing system is a new tool of gene editing technology based on the im-mune mechanism of archaea against foreign nucleic acid invasion. Due to its high efficiency and accuracy, CRISPR/ Cas9 genome editing technology has been widely used in tumor therapeutic research,such as targeted knockout of oncogenes,repair of tumor suppressor genes,breaking immune tolerance,and construction of tumor models,which brings revolutionary development to tumor gene therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of International Oncology
Year:
2018
Type:
Article
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