Research of Huangong decoction combined with routine treatment of western medicine for the postpartum hemorrhage and fundus reduced height of the postpartum hemorrhage / 国际中医中药杂志

ABSTRACT

Objective To research of Huangong decoction combined with routine treatment of western medicine for the postpartum hemorrhage and fundus reduced height of the postpartum hemorrhage (PPH). Methods A total of 242 patients with postpartum hemorrhage were enrolled and divided into two group by random number table: the treatment group (121 patients) and the control group (121 patients). Patients in the control group were treated with the western medicine routine treatment, while the treatment group were treated with Huangong decoction plus routine treatment. Both groups were treated for 3 days with a follow-up of 42 d. The postpartum haemorrhage amount, fundus height reduction were compared. The clinical effect rate was evaluated with postpartum haemorrhage amount, palace at the uterine bottom of the height reduction. Results The total clinical effectiveness rate of the treatment group was 97.5% (118/121), and the control group was 90.1%(109/121). The difference of two groups was statistically significant (χ2=4.478, P=0.034). After production, the uterine bottom height reduction at the first day (9.3 ± 1.4 mm vs. 8.0 ± 1.3 mm, t=7.501), the second day (10.2 ± 1.2 mm vs. 9.1 ± 1.1 mm, t=7.447) and the third day (12.2 ± 1.5 mm vs. 10.1±1.4 mm, t=11.283) in the treatment group were significantly greater than the control group (P<0.01). The postpartum hemorrhage at the first day (732.1 ± 84.3 ml vs. 766.4 ± 90.0 ml, t=-3.066), the second day (480.1 ± 62.0 ml vs. 590.0 ± 74.3 ml, t=-12.513) and the third day (240.4 ± 36.3 ml vs. 340.3 ± 52.0 ml, t=-17.351) in the treatment group were significantly less than the control group (P<0.01). After postpartumt, the uterine volume (632.1 ± 101.2 mm3 vs. 701.4 ± 135.7 mm3, t=-5.095) at third day and (142.3 ± 16.5 mm3 vs. 160.6 ± 19.7 mm3, t=-7847) at the follow-up, in the treatment group were significantly less than the control group (P<0.01). Conclusions The Huangong decoction combined with routine treatment of western medicine can improve the clinical symptoms in patients with PPH, and contribute to the recovery of disease.