Serum interleukin-31 level and pruritus in atopic dermatitis: A Meta-analysis / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 124-130, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-693786
ABSTRACT
Objective:
To investigate associations of interleukin-31 (IL-31) and pruritus in atopic dermatitis (AD) with Meta-analysis.Methods:
Materials were extracted from the citations listed in the following databasesPubMed,Science Direct,Web of Science and Cochrane.Key search terms includedatopic dermatitis,pruritus,and IL-31.The Meta-analysis was used to analyze the correlation between pruritws in AD and IL-31 expression level.Results:
The Meta-analysis showed that serum IL-31 levels were higher in AD patients than those in the healthy controls.The levels of IL-31 were higher in severe AD patients than those in the mild and moderate AD patients.Moreover,a positive correlation between serum IL-31 levels and severity of pruritus was identified.Conclusion:
Increased serum levels of IL-31 generally exist in the AD patients,and it may accelerate the pruritus in the AD patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Systematic reviews
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2018
Type:
Article
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