Survival analysis for high-grade glioma patients who received comprehensive treatment / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
;
(12): 388-393, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-693827
ABSTRACT
Objective:
To analyze the curative effect and prognostic factors for comprehensive therapy in patients with high-grade glioma.Methods:
Patients with high-grade glioma (WHO grade Ⅲ,grade Ⅳ) were chosen from July 2008 to May 2016 in the Hunan Cancer Hospital,and a retrospective analysis was performed in 64 patients with complete follow-up data.Results:
The follow-up time was 3-111 (median 29.5) months,the median overall survival time was 36.00 (95% CI 22.85 to 49.16) months,the median progression-free survival time (PFS) was 21.00 (95% CI 9.72 to 32.28) months,The 1-year,2-year,3-year and 5-year survival rates of high-grade glioma patients were 87.50%,56.25%,40.63% and 17.19%,respectively.The univariate analysis of Log-Rank test and the Cox regression model analysis showed that the prognostic factors related to the prognosis of high-grade glioma patients were pathological grade,resection degree,and concurrent chemo-radiotherapy (P<0.05).Conclusion:
The overall survival time,progression-free survival time and the 5-year survival rate of patients with high-grade glioma after comprehensive treatment is partially improved.The factors relevant to the prognosis of patients with high-grade glioma are pathological grade,resection degree,and concurrent chemo-radiotherapy,indicating that the glioma patients (WHO grade Ⅲ) received total resection of the tumor and concurrent chemo-radiotherapy have better clinical effect.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Prognostic study
Language:
Chinese
Journal:
Journal of Central South University(Medical Sciences)
Year:
2018
Type:
Article
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